Pengaruh Rebusan Simplisia Daun Sirih Merah Terhadap Penurunan Kadar Glukosa Darah Pada Penderita Diabetus Mellitus Di Panti Werdha Budi Mulia 2

Authors

  • Salsa Bian Rohbianti Universitas Yatsi Madani
  • Solihati Universitas Yatsi Madani
  • Adi Dwi Susanto Universitas Yatsi Madani

DOI:

https://doi.org/10.23969/jp.v11i03.67800

Keywords:

Keywords: diabetes mellitus; blood glucose level; red betel leaf simplicia decoction; Piper crocatum; complementary therapy.

Abstract

Diabetes mellitus is a non-communicable disease with an increasing prevalence that requires optimal blood glucose control. In addition to pharmacological treatment, complementary herbal therapy, such as a decoction of red betel leaf (Piper crocatum) simplicia, has the potential to serve as an alternative treatment because it contains flavonoids, alkaloids, tannins, and saponins, which exhibit antidiabetic properties through antioxidant activity, improved insulin sensitivity, and inhibition of glucose absorption.

This study aimed to analyze the effect of administering a decoction of red betel leaf simplicia on reducing blood glucose levels in patients with diabetes mellitus at Panti Werdha Budi Mulia 2.

This study employed a quantitative approach using a quasi-experimental pre-test with control group design. A total of 30 respondents were selected through purposive sampling and divided into intervention and control groups. Blood glucose data were collected through observation and measurement using a glucometer and analyzed using the Shapiro–Wilk, Wilcoxon, and Mann–Whitney tests.

The findings revealed a statistically significant difference in blood glucose reduction between the intervention and control groups (p = 0.001), indicating that the administration of red betel leaf simplicia decoction was effective in reducing blood glucose levels in patients with diabetes mellitus.

Therefore, red betel leaf simplicia decoction has the potential to be used as a complementary therapy for blood glucose management.

 

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References

Amazihono, I. K., & Waruwu, L. P. (2024). Pemberian air rebusan daun sirih merah untuk menurunkan kadar gula darah pasien diabetes mellitus. Jurnal Penelitian Kesehatan “Suara Forikes”, 15(3), 415. https://doi.org/10.33846/sf15313

American Diabetes Association. (2023). Standards of care in diabetes—2023. Diabetes Care, 46(Suppl. 1).

Anggoro, P. D., Badriah, D. L., & Mamlukah, M. (2025). Faktor-faktor yang berhubungan dengan kejadian diabetes melitus tipe 2 pada lansia. Jurnal Ilmu Kesehatan Bhakti Husada: Health Sciences Journal, 16(1), 242–250. https://doi.org/10.34305/jikbh.v16i01.1644

Estiningsih, D. (2025). Gambaran pola pengobatan dan komplikasi pada pasien DM tipe II di RSUD Panembahan Senopati Bantul. Inpharnmed Journal, 8(2). https://doi.org/10.21927/inpharnmed.v8i2.513565

International Diabetes Federation. (2024). IDF Diabetes Atlas (11th ed.).

Kadek Yunia Pratiwi, N., & Wayan Martadi Santika, I. (2023). Review artikel mekanisme aktivitas anti-diabetes dari kandungan senyawa tanaman kersen (Muntingia calabura L.): Systematic review, 2.

Kementerian Kesehatan RI. (2023). Survei Kesehatan Indonesia (SKI) 2023. Kementerian Kesehatan RI.

Nora, P., Gultom, N., Harahap, F., Edi, S., & Sipahutar, H. (2025). Hubungan antara jenis kelamin dan usia pada penyakit diabetes melitus di Puskesmas Kota Medan tahun 2024–2025. Jurnal Bioshell, 14(1), 142–150. https://doi.org/10.56013/bio.v14i1.3960

Perkumpulan Endokrinologi Indonesia (PERKENI). (2024). Pedoman pengelolaan dan pencegahan diabetes mellitus tipe 2 dewasa di Indonesia.

Rustiana, N., Pramudita, S., & Sekolah Tinggi Ilmu Kesehatan IKIFA. (2024). Analisa tingkat pengetahuan masyarakat tentang penyakit diabetes mellitus di RW 004 Kelurahan Pulogebang Kecamatan Cakung Jakarta Timur. Jurnal Farmasi IKIFA, 3(2).

Samapati, R. U. R., Putri, R. M., & Devi, H. M. (2023). Perbedaan kadar gula darah berdasarkan jenis kelamin dan status gizi (IMT) lansia penderita diabetes melitus tipe 2. Jurnal Akademika Baiturrahim Jambi, 12(2), 417. https://doi.org/10.36565/jab.v12i2.699

Saputri, & Riamah, R. (2025). Literature review: Pengaruh rebusan daun sirih merah untuk mengatasi diabetes melitus. Surya Medika: Jurnal Ilmiah Ilmu Keperawatan dan Ilmu Kesehatan Masyarakat, 20(1), 34–42. https://doi.org/10.32504/sm.v20i1.1241

Syahirah, N., & Berti Anggraini, R. (2025). Pengaruh air rebusan daun sirih merah terhadap kadar gula darah pada pasien diabetes melitus di Puskesmas Melintang Pangkal Pinang tahun 2024. Poltekkes Kemenkes Kepulauan Bangka Belitung, 6(1).

World Health Organization. (2022). Diabetes [Fact sheet].

Yusriana, Y., Kontesa, M., & Afrizal, A. (2025). Pengaruh pemberian rebusan daun sirih merah (Piper crocatum) terhadap kadar gula darah penderita diabetes melitus tipe II. Jurnal Keperawatan dan Kebidanan, 17(1), 33–42. https://doi.org/10.56586/jkk.v17i1.426

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Published

2026-09-22